Fig. 2: Rps27l inactivation reduces proliferation and enhances apoptosis upon radiation.

Inactivation of Rps27l inhibits proliferation and induces apoptosis upon radiation in small intestine. BrdU was i.p. injected into WT littermates and Rps27l mutants 2 h before mice being sacrificed. Small intestine tissues were harvested, followed by BrdU staining a and TUNEL assay b. Positive staining cells of each crypt were counted from at least three randomly selected microscopic fields from three independent mice (lower panels). *p < 0.05. Scale bars represent 100 µm