Fig. 4: MLN2238 treatment induces ER stress in HCC cells. | Cell Death & Disease

Fig. 4: MLN2238 treatment induces ER stress in HCC cells.

From: Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells

Fig. 4

Effects of MLN2238 treatment with 500 nM of MLN2238 for 24 h on ER stress gene expression levels were determined by quantitative Real-Time PCR a and semiquantitative PCR b. a The relative gene expression was calculated (ratio of drug-treated samples vs. control) and corrected by the quantified level of β-actin expression. b Expression of XBP1 mRNA. u = unspliced XBP1 mRNA; s = spliced XBP1 mRNA

Back to article page