Fig. 2: Phosphorylated nephrin recruites c-Abl in cultured podocytes. | Cell Death & Disease

Fig. 2: Phosphorylated nephrin recruites c-Abl in cultured podocytes.

From: Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II

Fig. 2: Phosphorylated nephrin recruites c-Abl in cultured podocytes.

Podocytes were transfected with myc-CD16/7-nephrin constructs and then stimulated with Ang II or CD16 antibody. a Double immunofluorescence staining of myc and c-Abl in different groups (original magnification, ×400). Scale bar = 10 μm. b, c Representative co-immunoprecipitation results of the interaction between myc and c-Abl in podocytes (n = 6). *p < 0.05 compared with Ang II-induced podocytes transfected with myc-CD16/7-nephrin constructs; #p < 0.05 compared with the CD16 antibody-pretreated podocytes transfected with myc-CD16/7-nephrin constructs. d Representative western blot of myc expression in podocytes transfected with vectors

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