Fig. 3: Nephrin phosphorylation restores Ang II-induced podocyte cytoskeleton reorganization. | Cell Death & Disease

Fig. 3: Nephrin phosphorylation restores Ang II-induced podocyte cytoskeleton reorganization.

From: Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II

Fig. 3: Nephrin phosphorylation restores Ang II-induced podocyte cytoskeleton reorganization.The alternative text for this image may have been generated using AI.

Podocytes were transfected with myc-CD16/7-nephrin constructs and then stimulated with Ang II or the CD16 antibody. a, c Representative migration results and quantification of different podocytes groups (n = 6). Scale bar = 100 μm. *p < 0.05 compared with control podocytes. #p < 0.05 compared with the Ang II-induced podocytes transfected with myc-CD16/7-nephrin constructs. b, d FITC-phalloidin staining and quantification of the cortical F-actin score for each group of differentiated podocytes (n = 6). Scale bar = 10 μm. *p < 0.05 compared with the podocytes treated without Ang II in each group. #p < 0.05 compared with the Ang II-induced podocytes transfected with myc-CD16/7-nephrin constructs

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