Fig. 3: Numbers of TNF-α+/IBA-1+ microglia are increased, while numbers of Arg-1+/IBA-1+ microglia are decreased, within the lesion sites of spinal cords of Hpx−/− mice after spinal cord injury. | Cell Death & Disease

Fig. 3: Numbers of TNF-α+/IBA-1+ microglia are increased, while numbers of Arg-1+/IBA-1+ microglia are decreased, within the lesion sites of spinal cords of Hpx−/− mice after spinal cord injury.

From: Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state

Fig. 3

a–d Representative images of TNF-α+/IBA-1+ (a, b) or Arg-1+/IBA-1+ (c, d) microglia in the spinal cord after crush injury on 4 (a, c) and 7 (b, d) dpl. e, f Quantification of the number of TNF-α+/ IBA-1+ (e) or Arg-1+/IBA-1+ (f) microglia in spinal cords from Hpx−/− and Hpx+/+ mice after crush injury. *p < 0.05, ***p < 0.005 compared with the indicated control. Scale bar = 30 µm. N = 6 mice per group at each time point

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