Fig. 7: Hpx regulated microglia polarization via an LRP-1-dependent pathway. | Cell Death & Disease

Fig. 7: Hpx regulated microglia polarization via an LRP-1-dependent pathway.

From: Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state

Fig. 7

a–d Effects of Hpx on the polarization of LPS-stimulated microglia were determined using quantitative RT-PCR. IL-1β, iNOS, and TNF-α were used as M1 markers (a–c) and Arg-1 was used as an M2 marker (d). e–k Scanning densitometry of TNF-α (e, g, i, k) and Arg-1 (f, h, i, j) levels, which were quantified and normalized to GAPDH. Data are presented as the means ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.005

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