Fig. 2: HMG20A protein expression is not altered in islets of high fat diet (HFD)-induced obesity and pre-diabetic mice. | Cell Death & Disease

Fig. 2: HMG20A protein expression is not altered in islets of high fat diet (HFD)-induced obesity and pre-diabetic mice.

From: The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity

Fig. 2: HMG20A protein expression is not altered in islets of high fat diet (HFD)-induced obesity and pre-diabetic mice.The alternative text for this image may have been generated using AI.

a Insulin tolerance test (ITT) and area under the curve (AUC) analysis in both control (CT) and HFD mice (CT, n = 10; HFD, n = 15). b Fasting blood glucose levels in both control and HFD mice (CT, n = 10; HFD, n = 15). c Representative images of pancreatic sections from HFD and CT mice stained and quantified for HMG20A (n = 4). d Hmg20a mRNA levels were assessed by qPCR in INS-1E cells cultured with 0.05 mM palmitate for 24, 48, 72 or 96 h (n = 3 independent experiments performed in triplicates). Data are represented as means + S.E.M. p values were determined by ordinary one-way ANOVA. *p < 0.05, **p < 0.01, ***p < 0.0001

Back to article page