Table 2 GO enrichment analysis of some ischemic stroke-related lncRNAs

From: Long non-coding RNAs in ischemic stroke

LncRNA

GO category

GO term

MEG3

Biological process

DEVELOPMENT: lung development; embryo development; post-embryonic development; skeletal muscle development; liver development; multicellular organism growth; determination of adult lifespan.

  

VASCULAR: angiogenesis; regulation of vascular endothelial growth factor receptor signaling pathway;

  

GENE REGULATION: RNA folding; DNA-templated transcription; DNA biosynthesis; hypomethylation of CpG island; DNA methylation; genetic imprinting.

  

INFLAMMATION: Notch signaling pathway; SMAD protein signal transduction.

  

CELL GROWTH: cell differentiation; negative regulation of cell proliferation.

  

OTHERS: axon guidance; gonadotropin secretion; epithelial tube morphogenesis.

 

Molecular function

Transcription co-activator activity.

 

Cellular component

Nucleus, cytoplasm.

MALAT1

Biological process

Nuclear speck organization; mRNA splicing; synapse organization; myoblast proliferation.

 

Molecular function

Protein binding.

 

Cellular component

Nuclear body, nuclear speck.

H19

Biological process

GENE REGULATION: DNA methylation; gene expression; genetic imprinting.

  

CELL GROWTH: regulation of multicellular organism growth; regulation of cell proliferation.

 

Cellular component

Polysome, cytoplasm.

TUG1

Biological process

Photoreceptor cell development.