Fig. 5: GRK5 knockdown inhibits A549 cell migration. | Cell Death & Disease

Fig. 5: GRK5 knockdown inhibits A549 cell migration.

From: GRK5 functions as an oncogenic factor in non-small-cell lung cancer

Fig. 5

a Wound-healing assay showed that knockdown of GRK5 inhibited the migration of A549 cells. Scale bar: 100 μm. b Relative width change (wound closure) comparing the 12 h width with 0 h starting width (%), quantification data for (a). c Knockdown of GRK5 decreased the migration ability of A549 by transwell assay. The OD570 number was indicated below for indicated images. Scale bar: 100 μm. d Quantification data for (c). e GRK5 depletion dramatically promoted vinculin staining positive numbers. Scale bar: 50 μm. f Quantification data for (c). *p < 0.05, **p < 0.01, ***p < 0.001, t-test

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