Fig. 12: β-catenin determines MEG3 suppressor function in vivo. | Cell Death & Disease

Fig. 12: β-catenin determines MEG3 suppressor function in vivo.

From: Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN

Fig. 12

A Tumorigenesis test in vivo. The mice were stratified and the tumors were recovered. The wet weight of each tumor was determined for each mouse. Each value was presented as mean ± standard error of the mean (SEM). **, P < 0.01. B The appearance time of each tumor was determined for each mouse. Each value was presented as mean ± standard error of the mean (SEM). **, P < 0.01. C A portion of each tumor was fixed in 4% paraformaldehyde and embedded in paraffin for histological hematoxylin–eosin (HE) staining and PCNA staining (DAB stainning, original magnification ×100).

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