Fig. 2: CAPN7 inhibits embryo implantation in vivo. | Cell Death & Disease

Fig. 2: CAPN7 inhibits embryo implantation in vivo.

From: Calpain7 impairs embryo implantation by downregulating β3-integrin expression via degradation of HOXA10

Fig. 2: CAPN7 inhibits embryo implantation in vivo.The alternative text for this image may have been generated using AI.

a Western blot analysis of uterine CAPN7 during the peri-implantation period in mice, with the strongest decreased signal detected at 4.5 dpc, when implantation begins. b Protein levels were normalized to GAPDH protein expression level (n is shown in each column, **p < 0.01 vs control). c Western blotting data showing uterine CAPN7 level after injection of Ad-GFP-CAPN7 or Ad-GFP. d Uteri from GFP-CAPN7-enhanced and control mice at 4.5 dpc of pregnancy were collected and stained with Chicago blue dye. The uteri were washed. The non-implanted blastocysts were then counted under a light microscope. Representative images are shown. e The number of implanted embryos was counted (n is shown in each column, ***p < 0.001 compared with control)

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