Figure 8: The elderly has higher non-classical monocyte count and plasma level of SASP cytokines. | Cell Death & Disease

Figure 8: The elderly has higher non-classical monocyte count and plasma level of SASP cytokines.

From: The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

Figure 8: The elderly has higher non-classical monocyte count and plasma level of SASP cytokines.

a Number of monocytes from each subset expressed as a percentage of the total number of monocytes. b Absolute number of monocytes from each subset present in a µL of whole blood. c TNF-α and IL-8 levels in the plasma, analyzed by Luminex assay. Each dot represents one donor; line represents median; (a–b) n = 30 each for both young and elderly individuals; (c) n = 20 for young, n = 30 for elderly; ***p < 0.001. CL: classical, ITM: intermediate, NC: non-classical

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