Fig. 6: Differential gene expression profile, gene ontology (GO) and signalling pathway analysis following il7r knockout. | Cell Death & Disease

Fig. 6: Differential gene expression profile, gene ontology (GO) and signalling pathway analysis following il7r knockout.

From: Knockout of zebrafish interleukin 7 receptor (IL7R) by the CRISPR/Cas9 system delays retinal neurodevelopment

Fig. 6

a The heat map of the differential gene expression profile following il7r knockout assessed by cDNA microarray. b and c The analysis of the top ten down-regulated GO (b) and signalling pathways (c). d Ten genes related to visual perception and phototransduction were selected to validate the microarray results. Results are represented as means ± SEM, ***P < 0.001. -Lg P: negative logarithm value of P values from differential gene expression by microarray

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