Fig.2: MiR-24/miR-221 promotes the TRAIL resistance of hepatocellular carcinoma cell

a–b miR-24 and miR-221 expression in TRAIL-sensitive or resistant HepG2 and Bel-7402 cells were determined using real-time PCR assays. c–d The mimics or inhibitor of miR-24 and miR-221 was transfected into HepG2R and Bel-7402R cells to achieve miRNA overexpression or miRNA inhibition, as confirmed using real-time PCR assays. e The cell apoptosis of the above cells were determined using flow cytometer assays. The data are presented as mean ± SD of three independent experiments. *P < 0.05; **P < 0.01, compared to control group; #P < 0.05; ##P < 0.01, compared to NC mimics or NC inhibitor group