Fig. 3: JQ1 and Bortezomib synergistically induce G2/M arrest through inhibiting FOXM1 expression. | Cell Death & Disease

Fig. 3: JQ1 and Bortezomib synergistically induce G2/M arrest through inhibiting FOXM1 expression.

From: Co-inhibition of BET proteins and NF-κB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions

Fig. 3: JQ1 and Bortezomib synergistically induce G2/M arrest through inhibiting FOXM1 expression.The alternative text for this image may have been generated using AI.

a, b qPCR analysis of G2/M checkpoint genes’ expression in HCT116, LoVo, and RKO cells after the treatment of indicated chemicals. c Western blot analysis of FOXM1 protein expression in HCT116 and LoVo cells after the treatment of indicated chemicals. d Immunohistochemical staining of FOXM1 in xenograft tumor sections of HCT116 cells. Bar, 100 μm

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