Fig. 2: DSB occurrence is related to DM formation | Cell Death & Disease

Fig. 2: DSB occurrence is related to DM formation

From: Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts

Fig. 2

. a IF shows increases of γH2AX foci in the Vec, CPX1, and CPX6 samples. Yellow: γH2AX; blue: DAPI; magnification ×1000. b The percentage of γH2AX foci in A, n = 30. c Western blot shows increases of γH2AX. d Quantification of the protein levels in c, n = 3. *P < 0.05

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