Fig. 4: The PI3K/Akt/BRCA1-A complex pathway is activated as the population of DM increases | Cell Death & Disease

Fig. 4: The PI3K/Akt/BRCA1-A complex pathway is activated as the population of DM increases

From: Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts

Fig. 4

. a Western blot results show increases in the PI3K/Akt pathway without the influence of PTEN as well as the reduction of BRCA1-A complex from Vec, CPX1, and CPX6 samples as DMs increase. b Quantification of the protein levels in a, n = 3. *P < 0.05; **P < 0.01; ***P < 0.001

Back to article page