Fig. 5: Galunisertib reduces the invasive growth capacity of HCC cells.

Invasive growth assay in 3-D culture. Representative images of spheroids obtained with HLE (a) and HLF (b) cells are shown in the left panel. The quantification of invasive growth capacity show (right panel) was calculated as the increase of the area occupied by the spheroids between day 0 and day 4. The line in the dot-plot graph represents mean value