Table 1 Relationship between intratumor PFKFB3 and clinicopathologic features
From: PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT
Variable | Ā | Intratumor PFKFB3 | ||
|---|---|---|---|---|
| Ā | Ā | Low expression | High expression | p |
Age (years) | Ā | 53.50 | 50.95 | 0.438 |
Gender | Female | 21 | 27 | 0.356 |
Male | 122 | 117 | Ā | |
HBsAg | Negative | 23 | 18 | 0.386 |
Positive | 120 | 126 | Ā | |
Cirrhosis | No | 113 | 106 | 0.281 |
Yes | 30 | 38 | Ā | |
AFP | ā¤20āng/ml | 49 | 34 | 0.047 |
>20āng/ml | 94 | 110 | Ā | |
Size (cm) | Ā | 5.36 | 5.67 | 0.040 |
Number | Single | 125 | 123 | 0.622 |
Multiple | 18 | 21 | Ā | |
Thrombus | No | 93 | 78 | 0.061 |
Yes | 50 | 66 | Ā | |
I | 85 | 68 | 0.046 | |
TNM | II | 38 | 58 | Ā |
III | 20 | 18 | Ā | |
Encapsulation | Yes | 72 | 70 | 0.768 |
No | 71 | 74 | Ā | |
Grade | I-II | 105 | 97 | 0.260 |
III-IV | 38 | 47 | Ā | |
