Fig. 2: Inhibition of HDAC family by HDI or specific inhibition of HDAC9 by si-HDAC9 rescued osteogenesis of P-PDLSCs. | Cell Death & Disease

Fig. 2: Inhibition of HDAC family by HDI or specific inhibition of HDAC9 by si-HDAC9 rescued osteogenesis of P-PDLSCs.

From: Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions

Fig. 2

a Protein expression level of HDAC9 and well-known histone targets of HDAC9 in untreated, NaB-treated P-PDLSCs. b Protein expression level of osteogenic markers RUNX2 and alkaline phosphatase (ALP). Comparison of osteogenesis in H-PDLSCs, P-PDLSCs, or NaB-treated P-PDLSCs 4 weeks after osteogenic induction by Alizarin red staining (c) or 7 days after induction by ALP staining (d). e–f RNA and protein expression levels of HDAC9 was analyzed between P-PDSLCs and si-HDAC9-treated P-PDLSCs. Analysis of protein expression level of osteogenesis marker RUNX2 (g) and calcified nodules by Alizarin red staining (h)

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