Fig. 5: Reducing PRC1 suppresses growth of HCC xenografts and improves efficacy of taxol against HCC.
From: Reducing protein regulator of cytokinesis 1 as a prospective therapy for hepatocellular carcinoma
a–d Tumor volumes of the HCC xenografts of HepG2 (a−c), or HuH-7 (d) cells receiving different Ads and/or taxol. The mice started to receive injections when the tumors reached 80 mm3 (a, b, d) or 200 mm3 (c) in volume. a−c are independent experiments. e Western blots for PRC1 and caspase-3 of different HCC xenografts. f H&E staining of xenograft samples; white arrows indicate the apoptotic cells with nuclear fragmentation. (*P < 0.05)
