Fig. 8: The miR-422a–PDK2 axis regulates ROS production through de novo lipogenesis. | Cell Death & Disease

Fig. 8: The miR-422a–PDK2 axis regulates ROS production through de novo lipogenesis.

From: MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer

Fig. 8

a Lipogenesis was measured by Oil-Red-O staining. b The cellular TAG concentration was quantified by employing a TAG detection kit. c FACS analysis (above) and statistical results (below) of ROS levels after treatment with 2 mg/L cerulenin or 0.7 mol/L Glycerol for 24 h. d Schematic for regulation of cellular metabolism and malignancy by the miR-422a–PDK2 axis in GC. The error bars represent the mean (n = 3) ± S.D. *P < 0.05, **P < 0.01, ***P < 0.001 versus corresponding NC

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