Fig. 1: Expression of PLAC8 in lung cancer and its association with clinicopathological features in lung cancer TMAs. | Cell Death & Disease

Fig. 1: Expression of PLAC8 in lung cancer and its association with clinicopathological features in lung cancer TMAs.

From: The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth

Fig. 1: Expression of PLAC8 in lung cancer and its association with clinicopathological features in lung cancer TMAs.

a PLAC8 mRNA (upper) and protein (lower) levels in seven LC cell lines were detected by Western blot and RT-PCR analysis. GAPDH was used as the loading control. b H1299 and H322 cells were stained for PLAC8 (green staining) and analyzed using fluorescence microscopy. Nuclei were stained with DAPI (blue staining). c Four representative images from the IHC analysis of PLAC8 expression (negative, weak, moderate, and strong) obtained from TMA LC samples. d The survival curve was compared using the Kaplan–Meier method according to the PLAC8 expression level. High PLAC8 was related to moderate and strong expression levels, while low PLAC8 was related to negative and weak expression levels. PLAC8 overexpression significantly predicted poor outcomes in LC patients (P = 0.0102). *P < 0.05

Back to article page