Fig. 2: PLAC8 silencing inhibited H322 and H1299 cell growth.
From: The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth
a The mRNA (upper) and protein (lower) expression of PLAC8 was downregulated in the PLAC8 knockdown cell lines H322 and H1299 compared with that in the negative controls. GAPDH served as the endogenous control. b Representative images of colony formation assays of the H322 and H1299 cell lines. PLAC8 silencing decreased the colony-forming efficiencies in both cell lines. c Knockdown of PLAC8 decreased the viabilities of the H322 and H1299 cell lines. d Quantification of the EdU incorporation rates in the PLAC8-silenced and control H322 and H1299 cell lines. Each bar represents the mean ± SD of three independent experiments. *P < 0.05 and **P < 0.01
