Table 3 Univariate and multivariate analysis of clinicopathological factors for OS and RFS

From: The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth

Univariate analysis

Variables

OS

 

HR (95.0% CI)

P value

Age (years)

1.007 (0.979–1.035)

0.635

Gender

0.946 (0.557–1.605)

0.836

Tumor size

1.112 (0.632–1.958)

0.713

Vessel invasion

1.043 (1.131–8.277)

0.968

LN metastasis

2.251 (1.301–3.896)

0.004*

Grade

3.086 (1.036–9.187)

0.043*

PLAC8

2.360 (1.404–3.965)

0.001*

Multivariate analysis

 LN metastasis

2.321 (1.365–3.946)

0.002*

 Grade

2.943 (1.035–8.366)

0.043*

 PLAC8

2.317 (1.402–3.830)

0.001*

  1. Note: Univariate analysis: log rank; multivariate Cox proportional hazards analysis
  2. OS overall survival, RFS relapse-free survival, HR hazard ratio, CI confidence interval, LN lymph node
  3. * Statistically significant (P < 0.05)
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