Fig. 1: DDX39 is an unfavorable prognostic factor for HCC patients. | Cell Death & Disease

Fig. 1: DDX39 is an unfavorable prognostic factor for HCC patients.

From: DDX39 promotes hepatocellular carcinoma growth and metastasis through activating Wnt/β-catenin pathway

Fig. 1

a DDX39 was upregulated in HCC tissues compared to normal liver tissues, data were downloaded from TCGA dataset. b Western blot analyzed DDX39 levels in normal liver cell and HCC cells. GAPDH was used as the loading control. c Western blot analyzed DDX39 levels in four pairs of HCC tissues (T) and matched normal liver tissues (N). GAPDH was used as the loading control. d IHC assay for DDX39 expression in normal liver tissues and HCC tissues with stage I–IV, representative images of IHC assay were shown. e Kaplan–Meier analysis of survival of HCC patients, patients whose tumors with DDX39 overexpression were labeled in red, and whose tumors with DDX39 underexpression were labeled in green. f Multivariate analyses of the prognostic value of DDX39 levels and other clinicopathologic characteristics, such as clinical stage, T stage, N stage, M stage, differentiation, cirrhosis, HBsAg, age and gender. *p < 0.05

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