Fig. 2: DDX39 overexpression promoted HCC cell migration and invasion. | Cell Death & Disease

Fig. 2: DDX39 overexpression promoted HCC cell migration and invasion.

From: DDX39 promotes hepatocellular carcinoma growth and metastasis through activating Wnt/β-catenin pathway

Fig. 2: DDX39 overexpression promoted HCC cell migration and invasion.The alternative text for this image may have been generated using AI.

a GSEA plot suggested DDX39 expression positively correlated with metastasis associated gene signatures using TCGA data. b Western blot analysis of DDX39 levels after DDX39 overexpression in Huh1 and Hep3B. GAPDH was used as the loading control. c Wound healing assay of the effect of DDX39 overexpression on HCC cell migration. d Transwell assay of the effect of DDX39 overexpression on HCC cell invasion. e 3D spheroid invasion assay of the effect of DDX39 overexpression on HCC cell invasion. Data are shown as means ± SD. *p < 0.05

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