Fig. 3: MiR-17-92 cluster promotes the production of chemokines in keratinocytes primed by cytokines. | Cell Death & Disease

Fig. 3: MiR-17-92 cluster promotes the production of chemokines in keratinocytes primed by cytokines.

From: MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis

Fig. 3: MiR-17-92 cluster promotes the production of chemokines in keratinocytes primed by cytokines.

a The mRNA levels of CCL20, CCL27, CXCL9, CXCL10, CXCL11, and CX3CL1 in NHKs with different treatments and transfections as indicated were analyzed using qRT-PCR. Mean ± SD is shown. Data are representative of three independently performed experiments. *P < 0.05; **P < 0.01; ns not significant. b The culture mediums of NHKs with different treatments and transfections as indicated were analyzed by ELISA to determine the secretion levels of CXCL9 and CXCL10. Mean ± SD is shown. Data are representative of three independently performed experiments. *P < 0.05; **P < 0.01; ***P < 0.001. c The migrations of CD3+ T cells in response to the culture mediums from NHKs with different treatments and transfections as indicated were evaluated using transwell assay. Mean ± SD is shown. Data are representative of three individual experiments. *P < 0.05; **P < 0.01; ***P < 0.001

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