Fig. 5: The expression of miR-17-92 cluster is increased in psoriasis lesions. | Cell Death & Disease

Fig. 5: The expression of miR-17-92 cluster is increased in psoriasis lesions.

From: MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis

Fig. 5: The expression of miR-17-92 cluster is increased in psoriasis lesions.

a The level of miR-17-92 cluster in perilesional skin (PLS) tissues and lesional skin (LS) tissues from 25 psoriasis patients and healthy skin (HS) tissues from 25 healthy controls was analyzed using qRT-PCR. Mean ± SD is shown. ***P < 0.001; ns not significant. b The correlation between PASI score and lesional miR-17-92 level in 25 psoriasis patients was analyzed using Spearman’s rank correlation test. c The level of miR-17-92 cluster in perilesional epidermis tissues and lesional dermis tissues from 10 psoriasis patients was analyzed using qRT-PCR. Each oblique line links the data from the same patient. ***P < 0.001. d The levels of miR-17, miR-18a, miR-19a, miR-19b, miR-20a, and miR-92a in perilesional skin (PLS) tissues and lesional skin (LS) tissues from 25 psoriasis patients and healthy skin (HS) tissues from 25 healthy controls were analyzed using qRT-PCR. Mean ± SD is shown. *P < 0.05; **P < 0.01; ***P < 0.001

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