Fig. 3: Inhibition of GCRL1 suppresses GC proliferation and metastasis in vivo. | Cell Death & Disease

Fig. 3: Inhibition of GCRL1 suppresses GC proliferation and metastasis in vivo.

From: Long noncoding RNA gastric cancer-related lncRNA1 mediates gastric malignancy through miRNA-885-3p and cyclin-dependent kinase 4

Fig. 3

a Tumor growth curves from day 9 to 29 after subcutaneous injection, with tumor volume calculated as 1/2 × length × width2 cm3. b Morphology of mice tumors dissected at day 29 after injection, n = 6 each group. c Tumor weight at day 29, n = 6 each group. d Expression levels of GCRL1 in mice tumor tissues detected by qRT-PCR, normalized to human GAPDH, n = 6 each group. e Left: photographs showing typical morphology of mice lungs dissected 29 days after tail vein injection (scale bars = 500 μm, n = 6 each group). Right: visualization of the dissected mice lungs with H&E staining and representative images were shown (scale bars = 100 μm). (f) Bar graphs showing the number of lung metastatic nodules per view, n = 6. Data are expressed as mean ± SD, *p < 0.05 compared to Lv-nc group (a, c, d, f)

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