Fig. 6: Twist1 or SNCG knockdown inhibits TGF-β-induced cell invasion. | Cell Death & Disease

Fig. 6: Twist1 or SNCG knockdown inhibits TGF-β-induced cell invasion.

From: Gamma synuclein is a novel Twist1 target that promotes TGF-β-induced cancer cell migration and invasion

Fig. 6

a HepG2 cells were transfected with 50 nM of indicated siRNA, followed by cell invasion assays in the absence or presence of TGF-β. Scale bar, 10 μm. The relative cell invasion rate was plotted. Values represent mean ± S.D. (n = 3). The invasion rate in siControl-transfected and TGF-β-untreated cells was set as 1. *p < 0.05; **p < 0.01. In parallel, the efficiency of Twist1 or SNCG knockdown was detected by western blotting. b HeLa cells were transfected with 50 nM of indicated siRNA, followed by cell invasion assays in the absence or presence of TGF-β. Scale bar, 10 μm. The relative cell invasion rate was plotted. Values represent mean ± S.D. (n = 3). The invasion rate in siControl-transfected and TGF-β-untreated cells was set as 1. *p < 0.05; **p < 0.01; ***p < 0.001. In parallel, the efficiency of Twist1 or SNCG knockdown was detected by western blotting

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