Fig. 1: CD24 expression is higher in tumor tissue samples of patients with poor prognosis.
From: CD24 regulates sorafenib resistance via activating autophagy in hepatocellular carcinoma
a, b Scatter plot of the CD24 and ABCG2 mRNA expression in tumor tissues and the corresponding adjacent tissues of HCC patients (n = 70). Patients with sorafenib resistance (13 of 70) had high expression of CD24. c The relative expression level of the CD24 protein in tumor tissues(T) and the corresponding adjacent tissues(P) of HCC patients. d The positive percent of CD24 was detected by IHC staining in 16 paraffin-embedded HCC and adjacent tissue specimens. The original magnification was ×200. e Patients with positive CD24 expression presented a poor overall survival (OS) compared with the negative group. Seventy patients were divided into the CD24 positive group (n = 32) and CD24 negative group (n = 38).Representative images are shown on the left, and quantitative data are on the right. Each experiment was performed in triplicate. Data are presented as the means ± s.e.m. and analyzed with the Student’s t-test (*P < 0.05, **P < 0.01)
