Fig. 6: Deregulating ANXA5 reduced the In vivo metastasis of Hca-P transplanted mice through CRKI/II and RAC1. | Cell Death & Disease

Fig. 6: Deregulating ANXA5 reduced the In vivo metastasis of Hca-P transplanted mice through CRKI/II and RAC1.

From: Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways

Fig. 6

IHC results shown ANXA5 was downregulation in tumor body both in 10 and 21 d (P= 0.001, A, Table 4). CRKI/II expression was suppressed in Hca-P-ANXA5-shRNA1 group in 21 d with significantly statistics (P = 0.041, B, Table 4). RAC1 expression had a decreased trend in 10d, and clear decrease in 21 d following transplantation (P = 0.013, C, Table 4)

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