Fig. 3: ARHGAP15 silencing facilitated the proliferation, migration, and invasion and induced S phase arrest of CRC cells.

LoVo cells were transfected with ARHGAP15 shRNA (sh-ARHGAP15) or control shRNA (sh-NC). a Cell proliferation detected by CCK-8 assay. b Cell cycle distribution analyzed by flow cytometry. c Cell migration detected by transwell assay. Scale bar: 100 μm. d Cell invasion detected by transwell assay. Scale bar: 100 μm. Experiments were repeated three times independently. NS: no significant difference; ** P < 0.01; *** P < 0.001