Fig. 8: Upregulation of HOXA-AS3 by histone acetylation in A549 cells.
From: Increased levels of the long noncoding RNA, HOXA-AS3, promote proliferation of A549 cells

a A549 cells were stimulated with varying concentrations of trichostatin A (TSA) for 24 h. b A549 cells were stimulated with varying concentrations of C646 for 24 h. c A549 cells were stimulated with varying concentrations of 5-aza-2′-deoxycytidine (5-AZA) for 24 h. d Binding of histone modifications to the HOXA-AS3 promoter region was examined using a chromatin immunoprecipitation (ChIP) assay in A549 cells. e Summary diagram describing how HOXA-AS3 regulates proliferation in A549 cells. *P < 0.05, **P < 0.01, and ***P < 0.001. All values are expressed as the mean ± SEM