Fig. 1: Modulation of cardiac-derived CTRP9 affects left ventricular dysfunction and myocardial infarct size after MI/R. | Cell Death & Disease

Fig. 1: Modulation of cardiac-derived CTRP9 affects left ventricular dysfunction and myocardial infarct size after MI/R.

From: Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis

Fig. 1

a–d Effect of cardiac CTRP9 deficiency upon left ventricular ejection fraction (LVEF), left ventricular end-systolic diameter (LVESD), and left ventricular end-diastolic diameter (LVEDD), determined by echocardiography. e TTC/Evans blue double staining. The left ventricular (LV) area, the area at risk (AAR), and ischemia area (IA) were measured. f–i Effect of cardiac CTRP9 overexpression upon LVEF, LVESD, and LVEDD. j Effect of cardiac CTRP9 overexpression upon myocardial infarct size. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01 vs. sham group; #P < 0.05, ##P < 0.01 vs. MI/R + NC group. N = 8–12

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