Fig. 7: CTRP9-KO rat displays a dysfunctional phenotype following MI/R injury, and cardiac CTRP9-pecific overexpression reverses acute cardiac injury. | Cell Death & Disease

Fig. 7: CTRP9-KO rat displays a dysfunctional phenotype following MI/R injury, and cardiac CTRP9-pecific overexpression reverses acute cardiac injury.

From: Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis

Fig. 7

a, b Cardiac CTRP9 expression in WT and CTRP9-KO rats receiving intra-myocardial injection of LV. CTRP9 or NC. c Representative echocardiograms with LVEF assessment of WT and CTRP9-KO rats subjected to MI/R. d Myocardial infarct size. e TUNEL staining. Bar = 40 μm. f–h Western blot analysis of PKA and CREB. Data are presented as mean ± SEM. $P < 0.05, $$P < 0.01 between the two groups connected by a line. N = 5–8

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