Fig. 3: Migration and invasion potential in vitro.

a, c Different migration potentials of the cell lines were detected by a wound healing assay. a Representative pictures (100×) of 0 and 12 h after scratching. c Statistic results of the percentages of wound healing. b, d A Transwell assay was conducted to compare the invasive potential of the cell lines. b Representative pictures (100×) of the migrated cells (“−FBS”, negative control). d Statistic results of the average invasive cells per field. Data shown are mean ± S.D. of three replicates. **p < 0.01, ***p < 0.001