Fig. 4: The response of penile cancer cell lines to cisplatin and EGFR-targeted drugs.

Cells were treated with cisplatin or EGFR-targeted drugs for 48 h. A CCK-8 assay was used to assess the relative cell viability. a Representative cisplatin dose-dependent cell viability. b The average IC50 values of cisplatin for the PSCC cell lines. c WB assays for EGFR expression (GAPDH was used as the loading control). d–f Representative cell viability curve after treatment with Cetuximab (d), Afatinib (e), or Erlotinib (f) (Caco or PC-9 cells were used as positive control)