Fig. 6: Role of NLRP3 inflammasome in hypoxia-induced cell death in human islets. | Cell Death & Disease

Fig. 6: Role of NLRP3 inflammasome in hypoxia-induced cell death in human islets.

From: NLRP3 inflammasome is expressed and regulated in human islets

Fig. 6

Human islets were incubated in control condition (Normoxia) or in 1% O2 hypoxia chamber (Hypoxia) for 24 h in the presence or absence of 200 μM glyburide (GLY). Cell death was evaluated by Apoptosense® ELISA kits. M65 values express both apoptosis and necrosis (a). M30 values express apoptosis (b). M65-M30 values (difference between the M65 and M30 values) express necrosis (c). NS no significant. Data are means ± SEM from seven experiments. *p<0.05

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