Fig. 1: Study outline and weight gain.

a Study outline. The weight was measured daily throughout the experiment. The entire period is shown in (b). A lag in weight gain was observed in the groups that received CIR (1). The montelukast groups weaned 1 day later than the vehicle groups (2). The days before and after CIR are zoomed in (c). CIR cranial irradiation, IHC immunohistochemistry. † = sacrifice. ncontrol vehicle = 10, ncontrol montelukast = 9, nCIR vehicle = 6, nCIR montelukast = 7. Statistical results from three-way ANOVA are presented in the figures, * = interaction between treatment, drug, and time. *P = 0.036