Fig. 3: Volumetric alterations following CIR and montelukast treatment. | Cell Death & Disease

Fig. 3: Volumetric alterations following CIR and montelukast treatment.

From: The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain

Fig. 3

a Investigated areas are highlighted in the schematic overview. The hippocampal regions are illustrated in b. The volumes were measured in the corpus callosum (c), thalamus (d), and hippocampal dentate gyrus (e). The subregions of the dentate gyrus; GCL (f), hilus (g), and molecular layer (h) are also presented. CC corpus callosum, CIR cranial irradiation, DG dentate gyrus, GCL granule cell layer, ML molecular layer, Th thalamus. c ncontrol vehicle = 7, ncontrol montelukast = 9, nCIR vehicle = 6, nCIR montelukast = 5. d ncontrol vehicle = 9, ncontrol montelukast = 9, nCIR vehicle = 6, nCIR montelukast = 7, e, f, g, h ncontrol vehicle = 8, ncontrol montelukast = 9, nCIR vehicle = 6, nCIR montelukast = 5. Error bars indicate ± SEM. Statistical results from two-way ANOVA are presented in the figures, ¤ = treatment (control/CIR), ¤P < 0.05

Back to article page