Fig. 1: PEAK1 enhances NSCLC cell migration and invasion in vitro. | Cell Death & Disease

Fig. 1: PEAK1 enhances NSCLC cell migration and invasion in vitro.

From: Overexpression of PEAK1 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling

Fig. 1

a Western blot analysis of PEAK1 protein expression in five human lung cancer cell lines. b After cells were infected with LV-PEAK1, LV-PEAK1-sgRNA and corresponding control vectors, the expression of PEAK1 protein was detected by western blot analysis. c The migration of 95D-Ctrl, 95D-PEAK1, H1299-Ctrl, and H1299-PEAK1 cells was detected by scratch wound-healing assay. d Invasion assay of 95D-Ctrl, 95D-PEAK1, H1299-Ctrl, and H1299-PEAK1 cells. e, f Migration and invasion assay of 95D-sgCtrl, 95D-KO, H1299-sgCtrl, and H1299-KO cells (two clones, c and d). Scale bar, 100 μm. *P < 0.05; **P < 0.01

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