Table 1 Clinical characteristics of 80 gastric cancer patients and AURKA/p27 expression

From: Suppression of AURKA alleviates p27 inhibition on Bax cleavage and induces more intensive apoptosis in gastric cancer

  

Aurora A and p27 expression

P

  

2H

1H1L

2L

Sex

  Male

63

54

7

2

0.191

  Female

17

15

2

0

Age (years)

  <60

27

22

5

0

0.071

  >=60

53

47

6

0

Tumor volume (cm3)

  <=5

46

40

6

0

0.203

  >5

34

29

3

2

Tumor location

  Up

19

15

4

0

0.687

  Middle

22

19

3

0

  Down

39

35

4

0

Pathological grade

  II

26

20

6

0

0.991

  II–III

25

25

0

0

  III

29

24

3

2

Invasion stage

  Mucosal and submucosal

1

1

0

0

0.372

  Muscular layer

8

7

1

0

  Serous membrane and outmembrane

71

61

8

2

Lymph node metastasis

  0

17

16

1

0

0.510

  1–6

36

29

7

0

  >=7

27

24

3

0

TNM stage

  I

5

5

0

0

0.031

  II

22

19

3

0

  III

46

41

3

2

  IV

7

4

3

0

Total

80

   

80

  1. P < 0.05 was considered statistically significant. Pearson’s chi-square test was used