Fig. 3: Effects of HIPK2 on the levels of inflammatory cytokines and oxidative stress-related markers in CLP-induced mice. | Cell Death & Disease

Fig. 3: Effects of HIPK2 on the levels of inflammatory cytokines and oxidative stress-related markers in CLP-induced mice.

From: Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy

Fig. 3

The CLP surgery was performed on the fifth day after the adenovirus injection and the liver and serum were obtained 16 h after CLP-induced sepsis. a, b, c Serum TNF-α, IL-1β and IL-6 concentrations were determined using ELISAs; data are presented as means ± SEM (n = 30 mice per group), #p < 0.05 compared with the sham plus Ad-vector group, + p < 0.05 compared with the CLP plus Ad-vector group. d–i Liver CAT (d), GSH (e), SOD (f), H2O2 (g), NO (h), and O.−2 (i) concentrations were measured using ELISAs; data are presented as means ± SEM (n = 30 mice per group), #p < 0.05 compared with the sham plus Ad-vector group, + p < 0.05 compared with the CLP plus Ad-vector group

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