Fig. 1: Ex vivo analysis of autophagic markers in GBM samples and patients’ overall survival. | Cell Death & Disease

Fig. 1: Ex vivo analysis of autophagic markers in GBM samples and patients’ overall survival.

From: Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

Fig. 1: Ex vivo analysis of autophagic markers in GBM samples and patients’ overall survival.

a Histological sections from GBM patients stained with hematoxylin/eosin or after immunostaining for BECN1, LC3, or SQSTM1 (p62). Avidin-biotin-peroxidase complex method lightly counterstained with hematoxylin. Original magnification 400×. b Kaplan-Meier curve generated by GraphPad software. Blu line indicates GBM patients with low levels of autophagy (LAL), while red line indicates GBM patients with high levels of autophagy (HAL). Statistical analysis: p = 0.0012; HR 0.3634; 95% CI from 0.1967 to 0.6715

Back to article page