Table 2 The correlation between Rab37, SFRP1, and Oct4 protein expression in lung cancer patientsa

From: Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness

Clinical parameters

Total patients

Rab37 protein expression

SFRP1 protein expression

Rab37/SFRP1 protein expression

 

109

N = 66 (60.6%) Preserved

N = 43 (39.4%) Low

N = 55 (50.5%) Preserved

N = 54 (49.5%) Low

N = 78 (72.2 %) Othersb

N = 30 (27.8 %) −/−

SFRP1 protein

Preserved

56

44 (78.6)

12 (21.4)

    

Low

53

22 (41.5)

31 (58.5) <0.001

    

Oct4 protein

Normal

45

32 (71.1)

13 (28.9)

31 (68.9)

14 (31.1)

38 (84.4)

7 (15.6)

High

63

34 (54.0)

29 (46.0) 0.077

24 (38.1)

39 (61.9) 0.002

40 (63.5)

23 (36.5) 0.018

  1. aThe data were analyzed by Pearson chi-squared test. P values are shown as superscripts with the significant ones shown in bold font.
  2. bOthers include patients with Rab37 and SFRP expression (+: preserved; −: low expression) according to the three molecular subtypes (+/+), (+/−), and (−/+). Rab37 expression is shown before the slash followed by SFRP1 expression
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