Fig. 2: MNA neuroblastoma cells are sensitive to the MRE11 inhibitor mirin.
From: MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors
a, b Effect of mirin treatment on cell viability of the indicated MNSC (open symbols) and MNA (black symbols) cells, and b MYCN+ and MYCN− SHEP Tet21/N cells, as measured by the MTS assay. c Effect of mirin treatment on colony formation assay in MYCN+ and MYCN− SHEP Tet21/N cells. For all panels, average data obtained by at least three independent experiments are reported as percentages compared to untreated controls, ±SD). p-Values were calculated by the Student’s t-test. *p < 0.05, **p < 0.01
