Fig. 4: Loperamide, pimozide, and STF-62247 induce dephosphorylation of mTOR and S6K.
From: Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells
MZ-54 WT cells were treated with 100 nM rapamycin, 100 ng/mL EGF, 20 µM IM/100 µM TIC, 17.5 µM loperamide, 15 µM pimozide, or 40 µM STF-62247 for the indicated time points followed by Western blotting with vinculin as loading control. UT untreated, EGF epidermal growth factor, IM imipramine hydrochloride, TIC ticlopidine, LOP loperamide, PIMO pimozide, STF STF-62247
