Fig. 6: Effect of Ngb overexpression on Dvl1 and β-catenin expression after stroke. | Cell Death & Disease

Fig. 6: Effect of Ngb overexpression on Dvl1 and β-catenin expression after stroke.

From: Neuroglobin promotes neurogenesis through Wnt signaling pathway

Fig. 6

To further investigate the involvement of Wnt signaling in Ngb-overexpression-induced neurogenesis, we tested the protein levels of Dvl1 and β-catenin in peri-infarct mice brain at 5 days after stroke. a Representative images of Western blot for Dvl1 and β-catenin from peri-infarct brain lysate; b, c Quantification of Dvl1 and β-catenin; d Representative images of Western blot for β-catenin from isolated nuclear protein; e Quantification of β-catenin in nuclear extract. (n = 4, *p < 0.05 vs sham, #p < 0.05 vs MCAO Lv-GFP)

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